| TMPY-02205
|
Beta-Catenin Protein, Human, Recombinant (His & GST)
|
Human |
Baculovirus-Insect Cells |
|
beta-Catenin, also known as CTNNB1, is a member of the armadillo family of proteins. These proteins have multiple copies of the so-called armadillo repeat domain, which is specialized for protein-protein binding. It is p... |
| TMPY-02985
|
Beta-Catenin Protein, Mouse, Recombinant (His & GST)
|
Mouse |
Baculovirus-Insect Cells |
|
beta-Catenin, also known as CTNNB1, is a member of the armadillo family of proteins. These proteins have multiple copies of the so-called armadillo repeat domain, which is specialized for protein-protein binding. It is p... |
| TMPY-06418
|
R-Spondin 2/RSPO2 Protein, Human, Recombinant (hFc)
|
Human |
HEK293 |
|
R-spondin-2, also known as RSPO2, synergizes with Wnt to activate beta-catenin. RSPO2 is secreted proteins that regulate beta-catenin signaling. Activator of the beta-catenin signaling cascade leads to TCF-dependent gene... |
| TMPY-01121
|
DKK3 Protein, Mouse, Recombinant (His)
|
Mouse |
HEK293 |
|
DKK3 (dickkopf related protein 3) is a member of the dickkopf-related family consisting of DKK1, DKK2, DKK3 and DKK4. It is a secreted protein, and also known as REIC (Reduced Expansion in Immortalized Cells). The DKK3 p... |
| TMPY-03626
|
R-Spondin 1/RSPO1 Protein, Human, Recombinant
|
Human |
CHO |
|
RSPO1 gene is a member of the R-spondin family. It encodes RSPO1 which is known as a secreted activator protein with two cystein-rich, furin-like domains and one thrombospondin type 1 domain. In mice, RSPO1 induces the r... |
| TMPY-01147
|
R-Spondin 1/RSPO1 Protein, Human, Recombinant (His)
|
Human |
HEK293 |
|
RSPO1 gene is a member of the R-spondin family. It encodes RSPO1 which is known as a secreted activator protein with two cystein-rich, furin-like domains and one thrombospondin type 1 domain. In mice, RSPO1 induces the r... |
| TMPY-03197
|
R-Spondin 1/RSPO1 Protein, Mouse, Recombinant (His)
|
Mouse |
CHO |
|
RSPO1 gene is a member of the R-spondin family. It encodes RSPO1 which is known as a secreted activator protein with two cystein-rich, furin-like domains and one thrombospondin type 1 domain. In mice, RSPO1 induces the r... |
| TMPY-04153
|
RNF43 Protein, Human, Recombinant (His)
|
Human |
HEK293 |
|
RNF43 mutations are frequently detected in colorectal cancer cells and lead to a loss of function of the ubiquitin E3 ligase. The outer mitochondrial membrane 34 (TOMM34) and ring finger protein 43 (RNF43) as highly expr... |
| TMPY-03722
|
EpCAM/TROP1 Protein, Cynomolgus, Recombinant (His)
|
Cynomolgus |
HEK293 |
|
Epithelial Cell Adhesion Molecule (EpCAM), also known as GA733-2 antigen, is a type I transmembrane glycoprotein composed of an extracellular domain with two EGF-Like repeats and a cystenin-rich region, a transmembrane d... |
| TMPY-02115
|
R-Spondin 3/RSPO3 Protein, Human, Recombinant (aa 1-146, His)
|
Human |
HEK293 |
|
R-spondin 3 (RSPO3) is a member of the R-Spondin (RSPO) family in vertebrates that activate Wnt/beta-catenin signaling, plays a key role in these processes. The RSPO family of secreted Wnt modulators is involved in devel... |
| TMPY-01300
|
EpCAM/TROP1 Protein, Human, Recombinant (His)
|
Human |
HEK293 |
|
Epithelial Cell Adhesion Molecule (EpCAM), also known as GA733-2 antigen, is a type I transmembrane glycoprotein composed of an extracellular domain with two EGF-Like repeats and a cystenin-rich region, a transmembrane d... |
| TMPY-02030
|
CD82 Protein, Human, Recombinant (His)
|
Human |
HEK293 |
|
CD82, also known as KAI-1, structurally belongs to tetraspanin family while categorised as metastasis suppressor gene on functional grounds. KAI1/CD82 is localized on cell membrane and form interactions with other tetras... |
| TMPY-05587
|
EpCAM/TROP1 Protein, Human, Recombinant (His & Avi), Biotinylated
|
Human |
HEK293 |
|
Epithelial Cell Adhesion Molecule (EpCAM), also known as GA733-2 antigen, is a type I transmembrane glycoprotein composed of an extracellular domain with two EGF-Like repeats and a cystenin-rich region, a transmembrane d... |
| TMPY-02118
|
IGFBP-6 Protein, Mouse, Recombinant (His)
|
Mouse |
HEK293 |
|
Insulin-like growth factor-binding protein 6 (IGFBP6) is a 24-kDa protein that binds insulin-like growth factor 1 (IGF-1) and IGF-2 with high affinity and inhibits IGF action in vitro. The Insulin-like growth factor-bind... |
| TMPY-04356
|
GSK3B Protein, Human, Recombinant (His)
|
Human |
Baculovirus-Insect Cells |
|
GSK3B is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It Contains 1 protein kinase domain, and is expressed in the testis, thymus, prostate, and ovary and weakly expressed in the lung, ... |
| TMPJ-01332
|
Frizzled-8 Protein, Human, Recombinant (His)
|
Human |
Human Cells |
|
Frizzled-8 is one of at least ten seven-transmembrane (7TM) glycoproteins of the Frizzled family of Wnt receptors. Frizzled proteins are thought to be G-protein-coupled. Wnt engagement, with low density lipoprotein recep... |
| TMPH-02436
|
5T4/TPBG Protein, Cynomolgus, Recombinant (E. coli, His & Myc)
|
Cynomolgus |
E. coli |
|
May function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization. |
| TMPJ-01331
|
Frizzled-8 Protein, Human, Recombinant (His & Avi), Biotinylated
|
Human |
Human Cells |
|
Frizzled-8 is one of at least ten seven-transmembrane (7TM) glycoproteins of the Frizzled family of Wnt receptors. Frizzled proteins are thought to be G-protein-coupled. Wnt engagement, with low density lipoprotein recep... |
| TMPY-00223
|
R-Spondin 2/RSPO2 Protein, Mouse, Recombinant (mFc)
|
Mouse |
HEK293 |
|
R-spondin-2, also known as RSPO2, synergizes with Wnt to activate beta-catenin. RSPO2 is secreted proteins that regulate beta-catenin signaling. Activator of the beta-catenin signaling cascade leads to TCF-dependent gene... |
| TMPY-04334
|
BAMBI Protein, Mouse, Recombinant (His)
|
Mouse |
HEK293 |
|
BMP and activin membrane-bound inhibitor (BAMBI) is a transmembrane glycoprotein that is a pseudoreceptor of type 1 receptors. BAMBI structurally lacks intracellular serine/ threonine kinase domain but with an extracellu... |
| TMPY-01456
|
BAMBI Protein, Human, Recombinant (His)
|
Human |
HEK293 |
|
BMP and activin membrane-bound inhibitor (BAMBI) is a transmembrane glycoprotein that is a pseudoreceptor of type 1 receptors. BAMBI structurally lacks intracellular serine/ threonine kinase domain but with an extracellu... |
| TMPH-02437
|
5T4/TPBG Protein, Cynomolgus, Recombinant (His & Myc)
|
Cynomolgus |
HEK293 |
|
May function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization. |
| TMPY-06377
|
DKK3 Protein, Human, Recombinant
|
Human |
HEK293 |
|
DKK3 (dickkopf related protein 3) is a member of the dickkopf-related family consisting of DKK1, DKK2, DKK3 and DKK4. It is a secreted protein, and also known as REIC (Reduced Expansion in Immortalized Cells). The DKK3 p... |
| TMPK-01001
|
RNF43 Protein, Mouse, Recombinant (hFc)
|
Mouse |
HEK293 |
|
RNF43 (E3 ubiquitin-protein ligase RNF43 or RING-type E3 ubiquitin transferase RNF43) functions as a tumor suppressor, by exerting a predominant negative feedback mechanism in the Wnt/β-catenin signaling pathway. RNF43 i... |
| TMPH-03756
|
Wint7b Protein, Human, Recombinant (His & Myc & SUMO)
|
Human |
E. coli |
|
Ligand for members of the frizzled family of seven transmembrane receptors that functions in the canonical Wnt/beta-catenin signaling pathway. Required for normal fusion of the chorion and the allantois during placenta d... |
| TMPH-01782
|
Norrin Protein, Human, Recombinant (GST & His & Myc)
|
Human |
E. coli |
|
Activates the canonical Wnt signaling pathway through FZD4 and LRP5 coreceptor. Plays a central role in retinal vascularization by acting as a ligand for FZD4 that signals via stabilizing beta-catenin (CTNNB1) and activa... |
| TMPY-04143
|
Chemerin/RARRES2 Protein, Mouse, Recombinant (hFc)
|
Mouse |
HEK293 |
|
Retinoic acid receptor responder protein 2 (RARRES2) is a small secreted protein involved in multiple cancers, including adrenocortical carcinoma (ACC). Serum RARRES2 may be used as a novel prognostic marker for ACC. Ret... |
| TMPY-03046
|
APCDD1 Protein, Human, Recombinant (hFc)
|
Human |
HEK293 |
|
Osteosarcoma (OS) is the most common type of bone tumor in children and adults. The expression of APCDD1, a Wnt antagonist, was reduced in OS tissues and cells compared to adjacent normal tissue and osteoblast cells, res... |
| TMPY-03127
|
BAMBI Protein, Mouse, Recombinant (hFc)
|
Mouse |
HEK293 |
|
BMP and activin membrane-bound inhibitor (BAMBI) is a transmembrane glycoprotein that is a pseudoreceptor of type 1 receptors. BAMBI structurally lacks intracellular serine/ threonine kinase domain but with an extracellu... |
| TMPY-04149
|
RNF43 Protein, Human, Recombinant (hFc)
|
Human |
HEK293 |
|
RNF43 mutations are frequently detected in colorectal cancer cells and lead to a loss of function of the ubiquitin E3 ligase. The outer mitochondrial membrane 34 (TOMM34) and ring finger protein 43 (RNF43) as highly expr... |
| TMPH-02861
|
Wnt7b Protein, Mouse, Recombinant (His & Myc & SUMO)
|
Mouse |
E. coli |
|
Ligand for members of the frizzled family of seven transmembrane receptors that functions in the canonical Wnt/beta-catenin signaling pathway. Required for normal fusion of the chorion and the allantois during placenta d... |
| TMPY-02094
|
R-Spondin 1/RSPO1 Protein, Human, Recombinant (aa 1-146, His)
|
Human |
HEK293 |
|
RSPO1 gene is a member of the R-spondin family. It encodes RSPO1 which is known as a secreted activator protein with two cystein-rich, furin-like domains and one thrombospondin type 1 domain. In mice, RSPO1 induces the r... |
| TMPH-02858
|
Wnt2 Protein, Mouse, Recombinant (His)
|
Mouse |
E. coli |
|
Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt/beta-catenin signaling pathway. Functions as upstream regulator of FGF10 expression. Plays an important role in e... |
| TMPY-00367
|
Chemerin/RARRES2 Protein, Mouse, Recombinant (His)
|
Mouse |
HEK293 |
|
Retinoic acid receptor responder protein 2 (RARRES2) is a small secreted protein involved in multiple cancers, including adrenocortical carcinoma (ACC). Serum RARRES2 may be used as a novel prognostic marker for ACC. Ret... |
| TMPJ-00163
|
R-Spondin 3/RSPO3 Protein, Human, Recombinant (hFc & His)
|
Human |
Human Cells |
|
R-spondin-3 (RSPO3), also known as Protein with TSP type-1 repeat, Roof plate-specific spondin-3, Thrombospondin type-1 domain-containing protein 2, PWTSR, THSD2 and CRISTIN1, is a member of the thrombospondin type 1 rep... |
| TMPY-01798
|
Frizzled 10 Protein, Mouse, Recombinant (His)
|
Mouse |
HEK293 |
|
Frizzled-1, also known as Fz-1, CD35 and FZD1, is a multi-pass membrane protein which belongs to theG-protein coupled receptor Fz/Smo family. Frizzled-1 / FZD1 is abundantly expressed in the cerebellum, followed by ce... |
| TMPY-04140
|
Frizzled 10 Protein, Human, Recombinant (hFc)
|
Human |
HEK293 |
|
Frizzled-1, also known as Fz-1, CD35 and FZD1, is a multi-pass membrane protein which belongs to theG-protein coupled receptor Fz/Smo family. Frizzled-1 / FZD1 is abundantly expressed in the cerebellum, followed by ce... |
| TMPH-02857
|
Wnt10a Protein, Mouse, Recombinant (His & Myc)
|
Mouse |
E. coli |
|
Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt/beta-catenin signaling pathway. Plays a role in normal ectoderm development. Required for normal tooth developmen... |
| TMPH-02864
|
Wnt1 Protein, Mouse, Recombinant (His & Myc)
|
Mouse |
E. coli |
|
Ligand for members of the frizzled family of seven transmembrane receptors. Acts in the canonical Wnt signaling pathway by promoting beta-catenin-dependent transcriptional activation. In some developmental processes, is ... |
| TMPY-01797
|
Frizzled 10 Protein, Mouse, Recombinant (hFc)
|
Mouse |
HEK293 |
|
Frizzled-1, also known as Fz-1, CD35 and FZD1, is a multi-pass membrane protein which belongs to theG-protein coupled receptor Fz/Smo family. Frizzled-1 / FZD1 is abundantly expressed in the cerebellum, followed by ce... |
| TMPY-01165
|
FZD1/Frizzled 1 Protein, Mouse, Recombinant (His)
|
Mouse |
HEK293 |
|
Frizzled-1, also known as FZD1, belongs to theG-protein coupled receptor Fz/Smo family. FZD1 contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, 7 transmembrane domains, and a C-term... |
| TMPJ-00268
|
5T4/TPBG Protein, Human, Recombinant (Avi & His), Biotinylated
|
Human |
Human Cells |
|
Trophoblast glycoprotein, also known as TPBG and 5T4, it belongs to the LRR family of proteins. The C-terminus of LRR N-terminal cap (LRRNT) and LRR 1 are essential for the inhibition of the Wnt signaling pathway. TPBG m... |
| TMPJ-01153
|
5T4/TPBG Protein, Cynomolgus, Recombinant (His)
|
Cynomolgus |
Human Cells |
|
Trophoblast glycoprotein, also known as TPBG and 5T4, it belongs to the LRR family of proteins. The C-terminus of LRR N-terminal cap (LRRNT) and LRR 1 are essential for the inhibition of the Wnt signaling pathway. TPBG m... |
| TMPY-04147
|
Frizzled 10 Protein, Human, Recombinant (His)
|
Human |
HEK293 |
|
Frizzled-1, also known as Fz-1, CD35 and FZD1, is a multi-pass membrane protein which belongs to theG-protein coupled receptor Fz/Smo family. Frizzled-1 / FZD1 is abundantly expressed in the cerebellum, followed by ce... |
| TMPY-06698
|
LRP-6 Protein, Human, Recombinant (His)
|
Human |
HEK293 |
|
Lipoprotein receptor-related protein 6 (LRP6) binds to Wnt ligands to transduce signal by stabilization of beta-catenin, which has been involved in the regulation of embryonic development and metabolism. Low density lipo... |
| TMPJ-00269
|
5T4/TPBG Protein, Human, Recombinant (mFc)
|
Human |
Human Cells |
|
Trophoblast glycoprotein, also known as TPBG and 5T4, it belongs to the LRR family of proteins. The C-terminus of LRR N-terminal cap (LRRNT) and LRR 1 are essential for the inhibition of the Wnt signaling pathway. TPBG m... |
| TMPY-06834
|
LRP-6 Protein, Human, Recombinant (hFc)
|
Human |
HEK293 |
|
Lipoprotein receptor-related protein 6 (LRP6) binds to Wnt ligands to transduce signal by stabilization of beta-catenin, which has been involved in the regulation of embryonic development and metabolism. Low density lipo... |
| TMPY-04441
|
CK2 alpha/CSNK2A1 Protein, Mouse, Recombinant (His & GST)
|
Mouse |
Baculovirus-Insect Cells |
|
Casein kinase II subunit alpha, also known as CK II alpha, CSNK2A1 and CK2A1, is a member of the protein kinase superfamily, Ser / Thr protein kinase family and CK2 subfamily. Casein kinase II (CSNK2A1) is a serine / thr... |
| TMPY-03134
|
REG3A Protein, Rat, Recombinant (His)
|
Rat |
HEK293 |
|
Regenerating islet-derived protein 3-alpha, also known as Regenerating islet-derived protein III-alpha, REG-3-alpha, REG3A, and HIP, is secreted protein that contains one C-type lectin domain. REG3A is constitutively exp... |
| TMPY-04144
|
Kremen-1 Protein, Human, Recombinant (His)
|
Human |
HEK293 |
|
KREMEN1 (Kringle Containing Transmembrane Protein 1) is a Protein Coding gene. This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (... |
